The U.S. researchers conducted a study to examine the effects of curcumin on cancer stem cells (CSCs) which cause tumors.
Cancer stem cells have the ability to renew themselves, which leads to the growth of tumor. Chemotherapy and radiotherapy are used as a cancer treatment. Researchers were unable to conclude why the CSC cells reappear after the treatment.
The evaluation of chemotherapy treatment efficacy and safety was done on a rodent model. Cancer stem cells, which reemerge after the treatment, are even more resilient, treatment-resistant, and lead to the death of a patient.
As conventional treatment further leads to the growth of harmful cancer cells, while it only kills less-harmful cancer cells, alternative solutions must be considered as a cancer treatment.
The effects of turmeric and curcumin extract in cancer treatment were the subject of many studies. Based on the latest findings, curcumin can be used to successfully target CSCs.
It seems that curcumin can influence CSC renewal in 12 different cancer cell lines. Curcumin has the ability to alter microRNA sequences in cancer stem cells, which lead to further suppression of tumor formation. Curcumin can also kill cancer cells without causing damage to healthy cells.
Based on all available research of the effect of curcumin on humans, researchers concluded that curcumin is not harmful to humans. It was concluded that curcumin has great potential in cancer treatment.
On the basis of tests which were conducted on rodents, curcumin has potential to inhibit CSCs causing glioma, breast, colorectal, pancreatic, brain, and esophageal cancers.
Further research will provide more information about the possible application of curcumin as a cancer treatment.